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Journal Article (15)

  1. Journal Article
    Papathanasiou, P.; Erdmann, S.; Leon-Sobrino, C.; Sharma, K.; Urlaub, H.; Garrett, R. A.; Peng, X.: Stable maintenance of the rudivirus SIRV3 in a carrier state in Sulfolobus islandicus despite activation of the CRISPR-Cas immune response by a second virus SMV1. RNA Biology 16 (4), pp. 557 - 565 (2019)
  2. Journal Article
    Maier, L. K.; Stachler, A. E.; Brendel, J.; Stoll, B.; Fischer, S.; Haas, K.; Schwarz, T.; Alkhnbashi, O. S.; Sharma, K.; Urlaub, H. et al.; Backofen, R.; Gophna, U.; Marchfelder, A.: The nuts and bolts of the Haloferax CRISPR-Cas system I-B. RNA Biology 16 (4), pp. 469 - 480 (2019)
  3. Journal Article
    Behler, J.; Sharma, K.; Reimann, V.; Wilde, A.; Urlaub, H.; Hess, W. R.: The host-encoded RNase E endonuclease as the crRNA maturation enzyme in a CRISPR-Cas subtype III-Bv system. Nature Microbiology 3 (3), pp. 367 - 377 (2018)
  4. Journal Article
    Buddeweg, A.; Sharma, K.; Urlaub, H.; Schmitz, R. A.: sRNA41 affects ribosome binding sites within polycistronic mRNAs in Methanosarcina mazei Gö1. Molecular Microbiology 107 (5), pp. 595 - 609 (2018)
  5. Journal Article
    Märtens, B.; Sharma, K.; Urlaub, H.; Bläsi, U.: The SmAP2 RNA binding motif in the 3'UTR affects mRNA stability in the crenarchaeum Sulfolobus solfataricus. Nucleic Acids Research 45 (15), pp. 8957 - 8967 (2017)
  6. Journal Article
    Cretu, C.; Schmitzova, J.; Ponce-Salvatierra, A.; Dybkov, O.; De Laurentiis, E.; Sharma, K.; Will, C. L.; Urlaub, H.; Lührmann, R.; Pena, V.: Molecular architecture of SF3b and structural consequences of its cancer-related mutations. Molecular Cell 64 (2), pp. 307 - 319 (2016)
  7. Journal Article
    Gleditzsch, D.; Müller-Esparza, H.; Pausch, P.; Sharma, K.; Dwarakanath, S.; Urlaub, H.; Bange, G.; Randau, L.: Modulating the Cascade architecture of a minimal Type I-F CRISPR-Cas system. Nucleic Acids Research 44 (12), pp. 5872 - 5882 (2016)
  8. Journal Article
    Shao, Y. M.; Richter , H.; Sun, S.; Sharma, K.; Urlaub, H.; Randau, L.: A non-stem-loop CRISPR RNA is processed by dual binding Cas6. Structure 24 (4), pp. 547 - 554 (2016)
  9. Journal Article
    Sharma, K.; Hrle, A.; Kramer, K.; Sachsenberg, T.; Staals, R. H. J.; Randau, L.; Marchfelder, A.; van der Oost, J.; Kohlbacher, O.; Conti, E. et al.; Urlaub, H.: Analysis of protein–RNA interactions in CRISPR proteins and effector complexes by UV-induced cross-linking and mass spectrometry. Methods 89, pp. 138 - 148 (2015)
  10. Journal Article
    Cass, S. D. B.; Haas, K. A.; Stoll, B.; Alkhnbashi, O. S.; Sharma, K.; Urlaub, H.; Backofen, R.; Marchfelder, A.; Bolt, E. L.: The role of Cas8 in type I CRISPR interference. Bioscience Reports 35 (3) (2015)
  11. Journal Article
    Hrle, A.; Maier, L. K.; Sharma, K.; Ebert, J.; Basquin, C.; Urlaub, H.; Marchfelder, A.; Conti, E.: Structural analyses of the CRISPR protein Csc2 reveal the RNA-binding interface of the type I-D Cas7 family. RNA Biology 11 (8) (2014)
  12. Journal Article
    Staals, R. H.; Zhu, Y.; Taylor, D. W.; Kornfeld, J. E.; Sharma, K.; Barendregt, A.; Koehorst, J. F.; Vlot, M.; Neupane, N.; Varossieau, K. et al.; Sakamoto, K.; Suzuki, T.; Dohmae, N.; Yokoyama, S.; Schaap, P. J.; Urlaub, H.; Heck, A. J. R.; Nogales, E.; Doudna, J. A.; Shinkai, A.; van der Oost, J.: RNA targeting by the type III-A CRISPR-Cas Csm complex of Thermus thermophilus. Molecular Cell 56 (4), pp. 518 - 530 (2014)
  13. Journal Article
    Plagens, A.; Tripp, V.; Daume, M.; Sharma, K.; Klingl, A.; Hrle, A.; Conti, E.; Urlaub, H.; Randau, L.: In vitro assembly and activity of an archaeal CRISPR-Cas type I-A Cascade interference complex. Nucleic Acids Research 42 (8), pp. 5125 - 5138 (2014)
  14. Journal Article
    Brendel, J.; Stoll, B.; Lange, S. J.; Sharma, K.; Lenz, C.; Stachler, A. E.; Maier, L. K.; Richter, H.; Nickel, L.; Schmitz, R. A. et al.; Randau, L.; Allers, T.; Urlaub, H.; Backofen, R.; Marchfelder, A.: A complex of Cas proteins 5, 6, and 7 is required for the biogenesis and stability of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-derived RNAs (crRNAs) in Haloferax volcanii. Journal of Biological Chemistry 289 (10), pp. 7164 - 7177 (2014)
  15. Journal Article
    Bhaskar, V.; Roudko, V.; Basquin, J.; Sharma, K.; Urlaub, H.; Seraphin, B.; Conti, E.: Structure and RNA-binding properties of the Not1-Not2Not5 module of the yeast Ccr4-Not complex. Nature Structrural and Molecular Biology 12 (20), pp. 1281 - 1288 (2013)

Thesis - PhD (1)

  1. Thesis - PhD
    Sharma, K.: Investigation of prokaryotic immune defense system with quantitative and structural mass spectrometry. Dissertation, 176 pp., Georg-August-Universität, Göttingen (2015)
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