Publikationen von R. Lührmann
Alle Typen
Zeitschriftenartikel (193)
Zeitschriftenartikel
29 (24), S. 2576 - 2587 (2015)
The large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation. Genes and Development
Zeitschriftenartikel
34 (24), S. 3059 - 3073 (2015)
Protein localisation by electron microscopy reveals the architecture of the yeast spliceosomal B complex. EMBO Journal
Zeitschriftenartikel
11 (9), e1005539 (2015)
Dynamic contacts of U2, RES, Cwc25, Prp8 and Prp45 proteins with the Pre-mRNA branch-site and 3' splice site during catalytic activation and step 1 catalysis in yeast spliceosomes. PLoS Genetics
Zeitschriftenartikel
21 (11), S. 1993 - 2005 (2015)
Stable tri-snRNP integration is accompanied by a major structural rearrangement of the spliceosome that is dependent on Prp8 interaction with the 5‘ splice site. RNA
Zeitschriftenartikel
125 (9), S. 3572 - 3584 (2015)
HDAC inhibitor-dependent transcriptome and memory reinstatement in cognitive decline models. Journal of Clinical Investigation
Zeitschriftenartikel
162 (3), S. 690 - 690.e1 (2015)
Snapshot: Spliceosome dynamics III. Cell
Zeitschriftenartikel
162 (2), S. 456 - 456.e1 (2015)
SnapShot: Spliceosome dynamics II. Cell
Zeitschriftenartikel
4, e07320 (2015)
A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing. eLife
Zeitschriftenartikel
161 (6), S. 1474 - 1474.e1 (2015)
SnapShot: Spliceosome dynamics I. Cell
Zeitschriftenartikel
22 (2), S. 138 - 144 (2015)
The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes. Nature Structural and Molecular Biology
Zeitschriftenartikel
29 (1), S. 94 - 107 (2015)
The G-patch protein Spp2 couples the spliceosome-stimulated ATPase activity of the DEAH-box protein Prp2 to catalytic activation of the spliceosome. Genes and Development
Zeitschriftenartikel
289 (50), S. 34683 - 34698 (2014)
Identification of small molecule inhibitors of pre-mRNA splicing. The Journal of Biological Chemistry
Zeitschriftenartikel
111 (44), S. 15622 - 15629 (2014)
Argonaute-1 binds transcriptional enhancers and controls constitutive and alternative splicing in human cells. Proceedings of the National Academy of Sciences of the United States of America
Zeitschriftenartikel
21 (10), S. 911 - 918 (2014)
Cooperative structure of the heterotrimeric pre-mRNA retention and splicing complex. Nature Structural and Molecular Biology
Zeitschriftenartikel
70 (6), S. 1622 - 1630 (2014)
Structural and functional analysis of the human spliceosomal DEAD-box helicase Prp28. Acta Crystallographica D
Zeitschriftenartikel
11 (4), S. 298 - 312 (2014)
Novel regulatory principles of the spliceosomal Brr2 RNA helicase and links to retinal disease in humans. RNA Biology
Zeitschriftenartikel
20 (3), S. 406 - 420 (2014)
Mass spectrometry–based relative quantification of proteins in precatalytic and catalytically active spliceosomes by metabolic labeling (SILAC), chemical labeling (iTRAQ), and label-free spectral count. RNA
Zeitschriftenartikel
21 (12), S. 2162 - 2174 (2013)
Phosphorylation drives a dynamic switch in serine/arginine-rich proteins. Structure
Zeitschriftenartikel
32 (21), S. 2804 - 2818 (2013)
RNA structure analysis of human spliceosomes reveals a compact 3D arrangement of snRNAs at the catalytic core. EMBO Journal
Zeitschriftenartikel
8 (9), e74851 (2013)
The Prp19 complex directly functions in mitotic spindle assembly. PLoS One