Publikationen von R. Brundiers
Alle Typen
Zeitschriftenartikel (4)
1.
Zeitschriftenartikel
304, S. 43 - 53 (2000)
Potentiating AZT activation: Structure of wild-type and mutant human thymidylate kinase suggest reasons for the mutants' improved kinetics with the HIV prodrug metabolite AZTMP. Journal of Molecular Biology 2.
Zeitschriftenartikel
8, S. 629 - 642 (2000)
Insights into the phosphoryltransfer mechanism of human thymidylate kinase gained from crystal structures of enzyme complexes along the reaction coordinate. Structure 3.
Zeitschriftenartikel
37, S. 3677 - 3686 (1998)
Crystal structure of yeast thymidylate kinase complexed with the bisubstrate inhibitor P1-(5′-adenosyl)P5-(5′-thymidyl) pentaphosphate (TP5A) at 2.0 Å resolution: Implications for catalysis and AZT activation. Biochemistry 4.
Zeitschriftenartikel
95, S. 14045 - 14050 (1998)
Structural basis for efficient phosphorylation of 3′-azidothymidine monophosphate by Escherichia coli thymidylate kinase. Proceedings of the National Academy of Sciences USA Hochschulschrift - Doktorarbeit (1)
5.
Hochschulschrift - Doktorarbeit
Protein-Design an Thymidylatkinasen zur Verbesserung des AZT-Monophosphat Umsatzes. Dissertation, Göttingen (1999)