Publications of Gesine Saher
All genres
Journal Article (34)
Journal Article
Downregulated expression of lactate dehydrogenase in adult oligodendrocytes and its implication for the transfer of glycolysis products to axons. Glia (2024)
Journal Article
16, pp. 616 - 640 (2024)
Targeting PI3K/Akt/mTOR signaling in rodent models of PMP22 gene-dosage diseases. Embo Molecular Medicine
Journal Article
223 (1), e201902050 (2024)
Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity. Journal of Cell Biology
Journal Article
46, pp. 59 - 78 (2023)
Cholesterol Metabolism in Aging and Age-Related Disorders. Annual Review of Neuroscience
Journal Article
26, pp. 1218 - 1228 (2023)
Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease. Nature Neuroscience
Journal Article
618, pp. 349 - 357 (2023)
Myelin dysfunction drives amyloid-β deposition in models of Alzheimer's disease. Nature
Journal Article
70 (11), pp. 2062 - 2078 (2022)
Diet triggers specific responses of hypothalamic astrocytes in time and region dependent manner. Glia
Journal Article
8 (37), eabo7639 (2022)
Ketogenic diet uncovers differential metabolic plasticity of brain cells. Science Advances
Journal Article
45 (4), pp. 272 - 283 (2022)
Local cholesterol metabolism orchestrates remyelination. Trends in Neurosciences
Journal Article
37 (4), 109889 (2021)
Neuronal cholesterol synthesis is essential for repair of chronically demyelinated lesions in mice. Cell Reports
Journal Article
3 (1), vdab140 (2021)
Anesthesia triggers drug delivery to experimental glioma in mice by hijacking caveolar transport. Neuro-Oncology Advances
Journal Article
24, pp. 47 - 60 (2021)
Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis. Nature Neuroscience
Journal Article
106 (1), pp. 37 - 65.e5 (2020)
Optimizing nervous system-specific gene targeting with Cre driver lines: prevalence of germline recombination and influencing factors. Neuron
Journal Article
68 (3), pp. 600 - 616 (2020)
Liver kinase B1 depletion from astrocytes worsens disease in a mouse model of multiple sclerosis. Glia
Journal Article
333, 108545 (2020)
Comparison of RNA isolation procedures for analysis of adult murine brain and spinal cord astrocytes. Journal of Neuroscience Methods
Journal Article
24 (10), pp. 1489 - 1501 (2019)
Uncoupling the widespread occurrence of anti-NMDAR1 autoantibodies from neuropsychiatric disease in a novel autoimmune model. Molecular Psychiatry
Journal Article
138, pp. 147 - 161 (2019)
Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus-Merzbacher disease. Acta Neuropathologica
Journal Article
5, 94 (2017)
Blood-brain barrier hyperpermeability precedes demyelination in the cuprizone model. Acta Neuropathologica Communications
Journal Article
8, 14241 (2017)
Dietary cholesterol promotes repair of demyelinated lesions in the adult brain. Nature Communications
Journal Article
5, 2934 (2016)
Inducible targeting of CNS astrocytes in Aldh1l1-CreERT2 BAC transgenic mice. F1000Research