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Substitution of Met-38 to Ile in γ-synuclein found in two patients with amyotrophic lateral sclerosis induces aggregation into amyloid. PNAS 102.
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Multiple redox switches of the SARS-CoV-2 main protease in vitro provide opportunities for drug design. Nature Communications 103.
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Rapid and synchronous chemical induction of replicative-like senescence via a small molecule inhibitor. Aging Cell, e14083 (2024)
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DescribePROT in 2023: more, higher-quality and experimental annotations and improved data download options. Nucleic Acids Research 107.
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Tail-tape-fused virion and non-virion RNA polymerases of a thermophilic virus with an extremely long tail. Nature Communications 108.
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Advancing cell biology with nanoscale fluorescence imaging: essential practical considerations. Trends in Cell Biology (2024)
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Multifaceted Role of the Substrate Phosphate Group in Transketolase Catalysis. ACS Catalysis 110.
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Highly cooperative chimeric super-SOX induces naive pluripotency across species. Cell Stem Cell 111.
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Hematologic parameters in female alpacas during age progression: a retrospective study. Scientific Reports 112.
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Ribosomal profiling of human endogenous retroviruses in healthy tissues. BMC Genomics 113.
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Guidelines for Free-Energy Calculations Involving Charge Changes. Journal of Chemical Theory and Computation 114.
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Nanobodies to multiple spike variants and inhalation of nanobody-containing aerosols neutralize SARS-CoV-2 in cell culture and hamsters. Antiviral Research 115.
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Vesicle condensation induced by synapsin: condensate size, geometry, and vesicle shape deformations. European Physical Journal E 116.
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Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity. Journal of Cell Biology 117.
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RNA polymerase II elongation factors use conserved regulatory mechanisms. Current Opinion in Structural Biology 118.
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Aggregation and beyond: alpha-synuclein-based biomarkers in synucleinopathies. Brain 119.
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Probing binding and occlusion of substrate in the human creatine transporter-1 by computation and mutagenesis. Protein Science 120.
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Phosphatases modified by LH signaling in ovarian follicles: testing their role in regulating the NPR2 guanylyl cyclase. Biology of Reproduction 121.
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Heating and cooling are fundamentally asymmetric and evolve along distinct pathways. Nature Physics 122.
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Mechanisms of SNARE proteins in membrane fusion. Nature Reviews Molecular Cell Biology 123.
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Isotope effect suggests site-specific nonadiabaticity on Ge(111)c(2×8). Natural Sciences 124.
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Hydrogen atom scattering at the Al2O3(0001) surface: a combined experimental and theoretical study. Physical Chemistry Chemical Physics 125.
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Regional AT-8 reactive tau species correlate with intracellular Aβ levels in cases of low AD neuropathologic change. Acta Neuropathologica 126.
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Interpretation of presynaptic phenotypes of synaptic plasticity in terms of a two-step priming process. Journal of General Physiology 127.
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The role of the HORMA domain proteins ATG13 and ATG101 in initiating autophagosome biogenesis. FEBS Letters 128.
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RNA helicase IGHMBP2 regulates THO complex to ensure cellular mRNA homeostasis. Cell Reports 129.
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Cocktail of lipophilic and hydrophilic chemotherapeutics in high-load core@shell nanocarriers to treat pancreatic tumours. Nanoscale Advances 130.
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Water dynamics in eutectic solutions of sodium chloride and magnesium sulfate: implications for life in Europa's subsurface ocean and ice shell. Physical Chemistry Chemical Physics 131.
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Synthesis and characterization of Fe3O4@SiO2@PDA@Ag core-shell nanoparticles and biological application on human lung cancer cell line and antibacterial strains. Artificial Cells, Nanomedicine, and Biotechnology 132.
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Drosophila MIC10b can polymerize into cristae-shaping filaments. Life science alliance 133.
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Distribution of Distances based Object Matching: Asymptotic Inference. Journal of the American Statistical Association 134.
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Dynamic assessment of scapholunate ligament status by real-time magnetic resonance imaging: an exploratory clinical study. Skeletal Radiology 135.
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Region-Specific Phosphorylation Determines Neuroligin-3 Localization to Excitatory versus Inhibitory Synapses. Biological Psychiatry, in press (2023)
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Conformational Dynamics of the Most Efficient Carboxylase Contributes to Efficient CO2 Fixation. Journal of Chemical Information and Modeling 137.
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Visualization of deglutition and gastroesophageal reflux using real-time MRI: a standardized approach to image acquisition and assessment. Scientific Reports 138.
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Experience with German Research Consortia in the Field of Chemical Biology of Native Nucleic Acid Modifications. ACS Chemical Biology 140.
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1,4-Benzothiazepines with Cyclopropanol Groups and Their Structural Analogues Exhibit Both RyR2-Stabilizing and SERCA2a-Stimulating Activities. Journal of Medicinal Chemistry 141.
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Probing the role of the C2F domain of otoferlin. Frontiers in Molecular Neuroscience 142.
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Ca2+ binding to the C2E domain of otoferlin is required for hair cell exocytosis and hearing. Protein & Cell, pwad058 (2023)
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Evaluation of MR-safe bioptomes for MR-guided endomyocardial biopsy in minipigs: a potential radiation-free clinical approach. European Radiology Experimental 147.
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The previously uncharacterized RnpM (YlxR) protein modulates the activity of ribonuclease P in Bacillus subtilis in vitro. Nucleic Acids Research 148.
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Multimodal interactions drive chromatin phase separation and compaction. Proceedings of the National Academy of Sciences of the United States of America 149.
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Depletion of preexisting B-cell lymphoma 2-expressing senescent cells before vaccination impacts antigen-specific antitumor immune responses in old mice. Aging Cell 150.
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Hyperpolarized Multi-organ Spectroscopy of Liver and Brain using 1-13C-Pyruvate Enhanced via Parahydrogen. Applied Magnetic Resonance